Alteration of Regional Homogeneity within the Sensorimotor Network after Spinal Cord Decompression in Cervical Spondylotic Myelopathy: A Resting-State fMRI Study

Brain Activity Map Extraction of Neuromyelitis Optica Patients Using Resting-State fMRI Data Based on Amplitude of Low Frequency Fluctuations and Regional Homogeneity Analysis

Introduction: Neuromyelitis Optica (NMO) is a rare inflammatory disease of the central nervous system which generally affecting the spinal cord and optic nerve. Damage to the optic nerve can result in the patient's dim vision or even blindness, while the spinal cord damage may lead to sensory and motor paralysis and the weakness of the lower limbs in the patient. Magnetic Reson...

Alteration of Brain Neural Network in Cervical Spondylotic Myelopathy Using Resting-state Functional Connectivity Mri

Amplitude of Low Frequency Fluctuation (ALFF) in the Cervical Spinal Cord with Stenosis: A Resting State fMRI Study

Cervical spondylotic myelopathy (CSM) is a common spinal cord dysfunction disease with complex symptoms in clinical presentation. Resting state fMRI (rsfMRI) has been introduced to study the mechanism of neural development of CSM. However, most of those studies focused on intrinsic functional connectivity rather than intrinsic regional neural activity level which is also frequently analyzed in ...

Human neuropathological and animal model evidence supporting a role for Fas-mediated apoptosis and inflammation in cervical spondylotic myelopathy.

Although cervical spondylotic myelopathy is a common cause of chronic spinal cord dysfunction in humans, little is known about the molecular mechanisms underlying the progressive neural degeneration characterized by this condition. Based on animal models of cervical spondylotic myelopathy and traumatic spinal cord injury, we hypothesized that Fas-mediated apoptosis and inflammation may play an ...

Predicting Unilateral Postlaminectomy C5 Palsy by Measuring C5 Exit Foramen Area on Preoperative Computed Tomography

Background. Postoperative C5 motor palsy is known as a common complication not only after cervical laminectomy but also after anterior discectomy. There is no consensus to verify any of the proposed mechanisms of C5 palsy following posterior cervical decompression. The authors of this article have found that C5 palsy is more common among patients with smaller C5 root exit foramen area. The purp...